BACKGROUND: Several technologies have been developed to aid dermatologists in the detection of melanoma in vivo including dermoscopy, multispectral digital skin lesion analysis (MDSLA), and reflectance confocal microscopy (RCM). To our knowledge, there have been no studies directly comparing MDSLA and RCM.
A clinical trial comprising 266 pigmented lesions and 49 vascular lesions has been performed in three Riga clinics by means of multi-spectral imaging analysis. The imaging system Nuance 2.4 (CRI) and self-developed software for mapping of the main skin chromophores were used.
Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm.
Paired comparison of the sensitivity and specificity of multispectral digital skin lesion analysis and reflectance confocal microscopy in the detection of melanoma in vivo: A cross-sectional study Author links open overlay panel Eunice Song BS b Jane M. Grant-Kels MD c Helen Swede PhD a b Jody L. D'Antonio CMA c Avery Lachance MD, MPH d Soheil S. Dadras MD, PhD c Arni K. Kristjansson MD c.
Multi-spectral imaging analysis of pigmented and vascular skin lesions: Results of a clinical trial. the decision of undergoing biopsy from the pigmented lesion using multispectral digital skin.
Multispectral Digital Skin Lesion Analysis Melanoma is a form of skin cancer that originates in the pigment-producing melanocytes. Most melanocytes produce melanin, and the tumors are commonly pigmented brown or black. Melanoma is less common than basal and squamous cell skin cancer, but it is more likely to metastasize than other skin cancers.
Impact of guidance from a computer-aided multispectral digital skin lesion analysis device on decision to biopsy lesions clinically suggestive of melanoma Darrell S. Rigel, Mrinalini Roy, Jane Yoo, Clay J. Cockerell, June K. Robinson, Richard White.
CONCLUSION AND RELEVANCE: An approach that integrates automated imaging technology like the Multispectral Digital Skin Lesion Analysis device, along with another diagnostic aid, with the end result being cost-effective, easy to use by even non-experts and comforting for the pediatric patient is likely to compete to be the new gold standard in successful early diagnosis and management of melanoma.